Were all these PSUs the same brand? How were the rails(5V, 12V) holding up before they died? Since 3 PSUs have died I would tend to suspect the mobo. Check to make sure all the mofsets are in place and everything is soldered on correctly. I had an Epox 8K3A in which one of the mofsets was soldered on incorrectly(it was diagonally soldered on to some other circuitry). Anyway, my system would keep powering down and ended up killing an Antec 480w PSU. Later, a close check of the board revealed this damaged mofset. BTW, did you hear any loud popping noises? Check out that mobo and make sure everything looks to be in place.