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Will isopropyl affect rubber gaskets or silicone sealant?

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yes it will, the seals will swell up and turn mushy over time, if you replace your seals frequently, you might try

but rubber especially don't hold up well to alcohol
 
uh-oh... i'm running 15% alcohol with a poly topped WW. Think I should switch to somthing elts? plus alcohol seems to leave a clearish white residue on my tube walls. good thing i'm just testing my system now so i can make any changes that i need to.
 
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