P5B DLX prep?

Should i do anything to the mobo before i start installing everything? should i do anything with the heatsinks/pipes on the chipsets? how many people put AS 5 on them? just trying to make sure i have everything covered before the board goes into the case.

I just replaced an ASROCK mbd with this board and I did have to remove a tray spacer nut which was differently placed to the locations of the P5B-Deluxe. My Apogee water block securing screws had to go in first of course. All seems OK apart from that. The little multiplugs for the mbd connectors are a real bonus for my cack handed installation skills.