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I would beware of the P45 Chipset at this time.
P45 boards are great for Ocing all types of CPU's, runs x-fire with dual x8 lanes just as well, no reason why you should not get one, there is absolutely nothing wrong with the chipset. I have two P45 boards (Asus P5Q3 and Gigabyte EP45-DS3R) and they both run great.
Give it a while
I sold my P5Q3 due to issues, and I have another P5Q Deluxe that's also starting to act weird....I posted a review a while back that explains some of it. And BTW, if you have or are planning on getting Raptors, that's another reason to overlook this immature chipset.
Link to the review, thanks...what issues did you see?, I believe people have some raid issues, fortunately I'm not a big raid fan.
So if you like both of those boards in DDR2...look at the DDR3 versions...DDR2 is dying pretty fast...better to upgrade the right way now instead of in a month or two later...
http://www.ocforums.com/showthread.php?t=565818
Actually, it all started off great....but over the course of a couple weeks, the situation started to go south...I did not post all (or even that many) of the problems I ran into, as they were many and occurred after I had posted the testing. But, likely the most serious, was the hard-drive issues that are occuring, namely a conflict between raptors (of any size, kind) and this board, and this includes a few different vendors, not just Asus. The P5Q3 and the P5Q were terrible overclockers, even with BIOS updates, and I believe they were "indirectly" responsible for my CPU degrading, since I was pumping more voltage through it trying to get it stable.
I am sure that it is possible that I got two, crappy boards, but that is unlikely.
In the future, the P45 may be a good choice for some when the bugs are worked out, but in the future we will have the x58 and the like, anyways
All in all, I would wait