P4B266 Memory Ratios

What would the difference in using the 1:1 or 4:3 memory ratios as applied to OCing?

P4 default fsb is 100MHz and memory running 1:1 =200MHz (DDR =2x100). Running async mode 4:3 forces memory channel to run 266MHz (2x133MHz). If You OC a lot You better change 1:1 if You think Your memory modules can not handle high MHz.

Thank you very much.