What you need to do is convince him that this program "needs" to be run whenever the computer is on. The easiest way to do that is to let him know about new generation of trojan virus. Let him know that new strains of these very damaging trojans are released every few hours and can wreck havoc on all parts of the computer, from the memory and hard drive to the floppy drive, CDR/RW even the lights on the front of the case will malfunction.
See to it that he is aware that these newest varieties can also infect the memory circiuts of your telephone if using a dial up modem or DSL and the television is at risk if using a cable modem. Once the virus gets into the telephone or cable lines it is very difficult to remove, sometimes the only remedy is the costly replacement of the actual lines within the walls of the house. I hope he doesn't live in a multi-unit apartment building or condo. By the way let him know that homeowners insurance will not cover this.
Let him know about the secret trojan anti-virus program that you are furtunate enough to be BETA testing right now, Selective Elimination of Trojan Infestion.
Be sure to explain to him that the latest strains of these virus are programmed to recognize anti-virus software, for this reason this new program makes no mention of it's anti-virus properties and it is cleverly disguised as a scientific research project. Show him how to read the results and what each means in relation to the trojan removal process (the interpretation is up to you).
Make sure that you let him know that the speed of the computer will determine how often the program needs to be updated (those virus writers sure are busy) and that this nifty little program will handle that all by itself.
If he buys into this, you can explain to him how much better this program would be able to do its job if he would let you increase the FSB and memory timings a little bit. For that matter explain how a bank of computers are that much more effective at eliminating the potential problems that a single machine may let slip through. The old adage, "strength in numbers", applies in this case.
In my case, my wife and kids are very much aware of how important the above situation is and will not even consider running one of these computers if that reassuring "SETI" anti-virus icon is not visable in the taskbar.
Good Luck!