Thete is a very good reason to have a fan here, but people commonly have an intake which is pointless unless you want to pull more dust into your case. Turn the fan so its exhausting out. The reason is that hot air can get trapped behind the motherboard, and an 80mm slim fan helps pull that hot air out of your case. An exhaust fan also keeps dust from going in behind your mobo.
Can you live without it? Of course. But fans are so cheap and quiet nowadays that this is one more step to help keep your system healthy (again, only if its pointed in the right direction). I invested in a nice motherboard and want to do all I can to protect that investment. If your case has a mounting bracket and perforations there then not having a fan is leaving an open hole. If you decide not to put a fan there then i recommend attaching a thin layer of filter screen inside the case door to keep grime from trickling in.
Besides, if you're on this forum you probably understand that every 2'C temp drop you can manage can only help, it all adds up to greater stability which means higher overclocks.