Small update.
I haven't tried to run Prime again yet, but I was able to get windows to load with the BLCK set to default.
But I changed the QPI Multi to 18, the UnCore Multi to 24, Mem Multi to 12, manaually set the timings, and changed the voltage to 1.590v (1.6v says on RAM) will try 1.605v next, since 1.600 wasn't available.
But with the manaual RAM settings, seems to be working, with all 12GBs (6x2GB) sticks in.
I'm going to run a memory test to confirm that the memory isn't the shutdown issue, and with these new settings working, I might be one step closer to getting the oc to work, if I can work out this shutdown issue.
Tried again, complete default like last night, it ran for a few moments longer, I was watching HWMonitor, nothing seemed to go too extreme, heat was barely hitting 60c voltages stayed pretty close to the max voltages that had shown for me running the PC for 30 minutes no stress test, so as soon as it starts to do something intensive, it shuts itself off...
Definitely starting to think its the PSU, or the BIOS update has changed the way some sort of power saving function works, although I turned off C-States and it still happened.
EDIT -
Spoke too soon, blue screened before I could do anything, BIOS settings stuck and it actually reloaded for once, so I went back in upped the CPU VTT to 1.23v (probs not a factor but why not), and the RAM up to 1.605v, blue screened again but now its running a windows repair thing, so will see if that fixes anything.