If you connect them is series, your northbridge and GPU would get warm water as it has already passes thru your CPU, AND the flowrate in the whole setup will also be slower because of the cumulative head/pressure losses from the three waterblocks (ie. water requires more pumping pressure as turbulence from irregular flow paths sap energy).
If you connect them in parallel, ALL three aforementioned components will receive cool water form the start. Water flow will be slower (only in each pair of the parallel tubing) because of the three-ways split and not primarily from head loss (as head loss is proportional to flowrate squared, and the flowrate is already slower to begin with). This means the flow of water going thru your radiator or bong will still be faster than that of the series connection.
Go for the parallel connection.