I suppose it depends on your setup which way you want to run it. I think that running them in parallel would be better, because each radiator gets the same temp water (the hotter the water, the more efficient the radiator), and so can cool it better than if you had two in series (because the first one will be doing most of the cooling, the second one will get cooler water, and so might drop a couple of decimal places out of the water temp).
If you run them in parallel, then the water will spend longer in the radiator (splitting the water in half, 1/2 the flow one way, 1/2 the flow the other, so the water will be going slower), so it will be better cooled.
Not really sure tho