Some of the standoffs on that linked page are for plastic. Some are for press fitting, and some are for threading in.
But again, I just drilled a smaller hole and drove them in with a nutdriver (like a socket on a screwdriver handle).
You can also tap plastic/plexi with a regular steel tap. Only use the tap for half of it's length, and the holes will grip nice an tight. If you use the tap all the way into the hole, you risk making the tapped holes too large, and stripping them easily.
You could also drill a regular hole that the threaded end fits into, and add some clear epoxy on the threads with a toothpick. Set the plastic sheet on waxpaper, and do them all at once.
If you want them removable, use some WD40 on a swab to "lube" the threads with first, then they should screw back out after the epoxy hardens. The epoxy will grip the holes in the plexi better if it's roughed up first with a small piece of 80 grit sandpaper first.
Dozens of ways, bud!