I really don't see the problem in running an online virus scan, especially since Symantec and Trend Micro are both reputable companies. AFA installing anti-spyware tools like SpywareBlaster, Microsoft AntiSpyware, or Spybot S&D...I don't understand why you would be leary about running any of those programs. If you don't feel comfortable running an online scan, there are a number of free versions of popular scanners available like AVG, Avast, and others....most of which you can find at MajorGeeks here:
http://www.majorgeeks.com/downloads29.html
In addition, we're only throwing out suggestions here. Without knowing anything about your system, other than you're running XP, myself and others can only hint at what the problem with your system might be. Both BrutalDrew and TalRW offered up excellent suggestions, but I can't see that you followed up on any of their advice, and if you did...I don't see any mention of it in your reply (other than your mention of running Spybot S&D at one time, which BTW isn't a virus scanner). You would also benefit more by at least making note of your system specs, including what hardware is installed. You could also include things like whether or not your system is overclocked, RAM timings, voltages, etc. Include in your summary what software you have installed, including any service packs, program updates, version numbers, etc.
Including such things in your post as 'when the problem started' would also be beneficial. I can offer up another suggestion to you re: troubleshooting, and that is to check the Event Viewer logs for any critical errors...
Start | Run | Type
eventvwr.msc and click OK | Highlight "Application" and "System" independently in the LH pane | Right click any error message(s) (critical errors are in
Red), and select "Properties" | Write down a couple of the latest critical error messages
exactly as they appear under the "Description" field, and post them in this thread. If you don't feel like writing them down ...when you right click an event and select "Properties", an "Information Properties" window will open. In the upper RH corner of the window is a button (just below the up/down arrow buttons) that when pressed copies the details of the event to the Clipboard. You can then paste the Clipboard contents of the logged error(s) in this thread.
Also, open the System Information tool by typing
msinfo32 in the Run box | Expand "Components" | Highlight "Problem Devices", and look for any problems that might be listed there.
Edit: You may also want to check out this sticky in the Networking forum...
Spyware/Malware & Security
http://www.ocforums.com/showthread.php?t=379516