Well you have two options. One is Drill it oversize and retap but that is probably not a good option. Option 2 is a bit more involved but it should work. Take one of the barbs and remove the O-Ring Wrap the barb once in teflon tape make sure you wrap the tape in the direction you would tighten the barb. Now you can either try to tighten it again which I don't reommend since it sounds like you stripped it pretty bad. OR
Get some JB weld mix it sparingly and spread it on the inside of the hole over the threads carefully. You don't need much at all just a dab will do you. A Very thin and I mean thin coat. once you have a nice very thin coat thread your barb into the hole about a 1/3 of the way. This is where you pay close attention to what the JB-Weld comes in contact with you may want to tape off most of the surrounding area of the hole. Ok so once you have the barb threaded in about half way. Leave it there for a about 20 minutes or so. Then remove the barb before it sets. It should leave some nice starter threads in the hole. If the teflon tape comes off so what, It is there to make sure you don't weld your barb into the hole permanently. it can stay there with no ill effects for now. Wait 24 hours then using the proper sized tap, (You will need to know what thread the barb you are using is), Re-tap the hole chasing the the threads you already made with your barb. This will ensure it is straight and clean up the threads and then cutting the rest of the threads at the bottom of the hole will give it strength. Flush the Radiator and then reattach the barb and tighten snugly and all should be well. That is what I would do.