You can have 24 nonremovable volumes with letters in NT derivatives (C through Z). Letters A & B are reserved for floppies, or, if you don't have floppies, removable drives of other types (external drives, flashcards, ZIP, etc.). There is no drive AA, CC, DD, etc. Mapped network drives, disks with multiple mounted partitions, etc., all count towards the letter limit when they're assigned one.
If you're really intent on having that many drives in your system and need to add more, mount the volume onto a folder, as you would in a UNIX derivative (e.g. /mnt/media ~= C:\volumes\media, which are filesystems on some specified drive; see this
MSKB article).
Just to be clear, this isn't a limit on the number of drives, rather the number of volumes mounted onto drive letters. You can have far more than 25, but eventually the drive letters run out and folders become the mount points.