Well, nothing in this world just lets you do as you please. For every action there is going to be some cost. In the case of a processor, there are a couple of factors to consider.
First off, going up from stock voltage, you will generally have more heat to deal with. If your cooling solution is not up to the amount of heat that you are dealing with, then you will eventually overheat your processor. When that happens, there are a few things that can happen depending on the design of your processor.
*Now I am not very up on the San Diego core just yet but generally speaking, if you get lucky, it just does not work quite right over some critical temperature. Then Windows will crash on you.
*Slightly worse can be what Intel is known for doing and that is to put a circuit in that underclocks your computer before it gets to a bad temperature. I have never known AMD to do that but as I say, I am not current on the matter.
*Beyond that is your really bad possibility. If you push it hard enough, the processor could fail totally and never restart again. When this happens you often let out the magic smoke that make processors work in the first place.
Now, the above in only true for high temperatures. If you are using a higher end cooling system that can handle what you throw at it, then yo run another risk. Every processor has a certain limit that you can throw at it before you again let out the magic smoke.
For any given core, there is a certain point at which they will generally fail but it can vary slightly from one chip to another. Usually, you will get some instability before that happens but there are always a few unlucky individuals who will trash a given chip before that happens.
To be honest, your best bet would be to post this question in the AMD CPU forum as there you are more likely to find people who have experience with pushing your core to the limit. When you do post there, it will really help if you give us the numbers that are written on your chip as that will identify it more clearly. Generally, the numbers can tell us what factory it came from, what week it was made and so on. The more info that you can give us the better.
Edit, I like your sig. But just remember what usually happend on "Tool Time".