"Cool" idea,
I think there will be more problems associated with the erratic pressure drops that the pump and loop might sustain whenever you are tossing and turning about, and getting in and out of bed everyday. Imagine being able to squeeze water in your loop through a reservoir bladder... both in the direction of the flow in the loop and AGAINST it. You could induce "dead" spots in the loop whenever you move on the bed.
I also agree with the comments surrounding water temperature, because that bed is not going to be pleasant in the winter months, and even at night during the hot summer... I have my window fan on auto-off because it gets too cold even though it is 90+ during the day.
But do not let anyone discourage your creativity and enthusiasm... most of all I would like to see this done too! Imagine the nerd-points you will acquire, by being able to integrate your computer life with you 24/7... the ladies will just be lining up!
If you decide to go through with it, good luck and keep as posted.
bryan d