yeah, for Quads, you'd want to go with a high end cooler because they put out far more heat than any dual core.
you also may want to consider some new HS that have come out recently
Xigmatek Thors Hammer
Megahalems.
these 2 are pretty beasty.
EDIT:
also if you get a TRUE, be sure to get some high static pressure fans, to help air get pushed through the tiny gaps between each fin.