ok, so let's get an idea or a drawing of sorts of what you would like
monitor space required?
speakers, are they mounted above or below? Do you have the types that can mount on a wall (like the Logitech satellites that come with the Z2300/5500?)
CPU, where is it located? on the top of the desk? under?
Other things like printers/scanners, etc that need to be considered?
how much space do you have for a desk, width/depth/height?