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Stanford scientists and collaborators boost potency, reduce side effects of IL-2

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'Cuda340

'Cuda340

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Regurgitating more of Vijay Pande's blog:

Stanford scientists and collaborators boost potency, reduce side effects of IL-2 protein used to treat cancer

Today, I'm highlighting the work primarily out of Chris Garcia's lab at Stanford Medical School. The Garcia lab had a very exciting idea on how to re-engineer a very important protein and the Pande lab played a part by providing computer simulations to help understand the mechanism by which the new protein worked. The results are very exciting. Check out the link below for more details.

http://medicalxpress.com/news/2012-03-scientists-boost-potency-side-effects.html

SUMMARY. The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist has generated a mutant version of the protein whose modified shape renders it substantially more potent than the natural protein while reducing its toxicity.
Click to expand...


Garcia Laboratory

Source

:cool:
 
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Brilliant! :clap:

Only one, in a long, long line of help for medical research. That's why we fold - we can't wait around for the government or the drug companies to do it all - they can't do it by themselves.
 
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