Yea, just don't assign the throttle to scrool wheel, lol.
Personally, I find that it works PERFECTLY for counter-strike. Mainly because of the few weapons.
It worked great in UT2003 for anything insta-gib.....beyond that it gets complicated. I use the thumb control for jump, crouch, walk, etc....the problem lies with the keys. It has 10, minus 4 for movement, and you're left with 6 keys. You can get around this with the shift feature which gives it essentially 40 keys....but that gets complicated as well. I suppose if you get used to it, it would work well, but it would take a bit of getting used to.
What I like about the n50 is that it's the size of your hand. Its not like those other controllers that are the size of your keyboard with almost the same number of buttons.....kinda defeats the purpose.