There seems to be a workaround for Phenom/Athlon, try it at your own risk (got it from the steam forums, google-translated from russian):
"This problem occurs on processors that do not use the SSE4.1 command set. In order to run the game on an unsupported processor, you must:
1) Download from here the emulator SSE. sde-external-7.49.0-2016-07-07-win (
https://software.intel.com/system/files/managed/2f/ac/sde-external-7.49.0-2016-07-07-win.tar.bz2).
2) Next, unpack the downloaded archive into the folder with the game. That sde.exe was in one folder with FarCry5.exe;
3) Create a shortcut from sde.exe. Open the properties of the shortcut and in the object parameter there will be written something like "Far Cry 5 \ Binaries \ sde.exe" adding this parameter to the line -- FarCry5.exe
It should look something like "D: \ Games \ Far Cry 5 \ bin \ sde.exe" -- FarCry5.exe
Pay attention, it is necessary to take into account two minuses together and a space after them.
Also, in the compatibility parameters of the shortcut it is worthwhile to put the option "run as administrator".
4) Now you can start the shortcut. A console window will open with the name sde.exe (you can close it). A couple of minutes may seem that nothing happens but then the game starts."
"Try to download Nvidia Profile Inspector, it needs to do the manipulations that are described in this video (
) If this did not help, try downloading a more recent version of the sde emulator.*And if this does not work, then I don’t even know what solution can be offered."