Compression are much better than barbs. If you use metal clamps, the clamps leave the ugly forms in the tubing. Compression fittings don't do that. Compression fitting look much better than barbs with clamps, plain and simple.
It's your choice. 2-3 dollars for barbs or 6-8 dollars or more for compression. Once i went to compression, I'd never use a barb again. I don't care about the cost.
Neither is safer than the other. If you do either wrong, you'll have leaks. Compression fittings do look 100% better and more professional than clamps and barbs.