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Senior Member
Jul 29, 2001
Warren, OH
Want to help the world? Look here!! Folding Team32

We are team 32 and the Folding@Home software can be found at

We are currently in competition with a few other teams. Only three are outproducing us at the moment and we could use your help to retake the lead that we once had. The article below contains information and links to information about the project to help you gain an understanding of exactly what it is that we are doing.

Originally posted by YMAN

Hello ALL fellow Overclockers.com members,
I am here today to talk to you about the Folding @ Home project. The Folding @ Home project is a software program
operated and managed by Stanford University. The Folding @ Home program simulates protein folding. Understanding Protein Folding
will get us years ahead in the research of finding cures for
diseases!!! Protein Folding is done rapidly within us, but it takes
computers LONG periods of time to reproduce these complicated
Folds. This is the reason Stanford University created a Protein
Folding program for us to use on our computers. The more
processors that are used the faster we research and find cures
for diseases! The program only uses your CPUs extra cycles so
you will not even know that it is running! So why not join the
Overclockers.com Folding team? WE NEED EVERYONE to
participate! Show your Overclockers.com spirit and find cures
for diseases.

Below is an In-Depth look at the Folding @ Home project:

PROJECT GOALS: Solving the protein folding problem

Understanding how proteins self-assemble ("protein folding") is a holy grail of modern molecular biophysics. What makes it such a great challenge is its complexity, which renders simulations of folding extremely computationally demanding and difficult to understand. (See Scientific Background for more details about what are proteins, why do they fold, why this is so difficult, and why do we care).

Our group has developed a new way to simulate protein folding ("distributed dynamics") which should remove the previous barriers to simulating protein folding. However, this method is extremely computationally demanding and we need your help (see below). We have already demonstrated that our distributed dynamics technique can fold small protein fragments and protein-like synthetic polymers. The next step is to apply these methods to larger, considerably more important and complicated proteins. Unfortunately, larger proteins fold slower and thus we need more computers to simulate their folding. While the alpha helix folds in 100 nanoseconds, proteins just a little larger fold 100x slower (10 microseconds). Thus, while 10-100 processors were enough to simulate the helix, we will need many more to simulate these larger, more interesting proteins.

To achieve a significant speedup, we need lots of processors in a given run. Also, since a single run does not tell us much, we need to simulate several runs (10 runs would be a good start) per protein. Thus, we need lots of processors. By running our client that uses the Mithral CS-SDK, you can lend us your machine for as long as you like. The client allows you to run for as little or as long as you like. Even a single day's worth of running is helpful to us.


Proteins are necklaces of amino acids --- long chain molecules. Proteins are the basis of how biology gets things done. As enzymes, they are the driving force behind all of the biochemical reactions which makes biology work. As structural elements, they are the main constituent of our bones, muscles, hair, skin and blood vessels. As antibodies, they recognize invading elements and allow the immune system to get rid of the unwanted invaders. For these reasons, scientists have sequenced the human genome -- the blueprint for all of the proteins in biology -- but how can we understand what these proteins do and how they work?


Since proteins play such fundamental roles in biology, scientists have sequenced the human genome. The genome is in a sense a "blueprint" for these proteins -- the genome contains the DNA code which specifies the sequence of the amino acids beads along the protein "necklace."


However, only knowing this sequence tells us little about what the protein does and how it does it. In order to carryout their function (eg as enzymes or antibodies), they must take on a particular shape, also known as a "fold." Thus, proteins are truly amazing machines: before they do their work, they assemble themselves! This self-assembly is called "folding."

One of our project goals is to simulate protein folding in order to understand how proteins fold so quickly and reliably, and to learn how to make synthetic polymers with these properties. Movies of the results of some of these simulation results can be found here.

PROTEIN FOLDING AND DISEASE: CJD (Mad Cow), Altzheimer's, ...

What happens if proteins don't fold correctly? Diseases such as Alzheimer's disease, cystic fibrosis, CJD (Mad Cow disease), an inherited form of emphysema, and even many cancers are believed to result from protein misfolding.

When proteins misfold, then can clump together ("aggregate"). These clumps can often gather in the brain, where it is believed to cause the symptoms of Mad Cow or Alzheimer's disease.

PROTEIN FOLDING AND NANOTECHNOLOGY: Building man made machines on the nanoscale

In addition to biomedical applications, learning about how proteins fold will also teach us how to design our own protein-sized "nanomachines" to do similar tasks. Of course, before nanomachines can carry out any activity, they must also be assembled.


It's amazing that not only do proteins self-assemble -- fold -- but they do so amazingly quickly: some as fast as a millionth of a second. While this time is very fast on a person's timescale, it's remarkably long for computers to simulate. In fact there is a 1000 fold gap between the simulation timescales (nanoseconds) and the times at which the fastest proteins fold (microseconds).


To solve the protein folding problem, we need to break the microsecond barrier. Our group has developed a new way to simulate protein folding which can break the microsecond barrier by dividing the work between multiple processors in a new way -- with a near linear speed up in the number of processors. Thus, with 1000 processors, we can break the microsecond barrier and unlock the mystery of how proteins fold.


Folding@Home 1.0 has been a success. During the one year period from October 2000 to October 2001, we have folded several small, fast folding proteins, with experimental validation of our method. We are now working to further develop our method, and to apply it to more complex and interesting proteins and protein folding and misfolding questions.


A good place to start to learn about some of our success with Folding @ Home 1.0 as well as how Folding @ Home works is with some of our recent papers. Our recent paper in Physical Review Letters describes the basis of our method as well as some mathematical justifications for how we can use tens to hundreds of thousands of PCs to speed folding simulations tens to hundreds of thousands of times. Our recent paper in The Journal of Molecular Biology discusses a little more about the specifics of our method as it applies to proteins as well as our first results --- the folding of a beta hairpin.

Still not convinced?
Well this is also a competition to see with team can fold the
most! We are currently in the top 5! This is also a competition
to find who can fold the most on the overclockers.com team!
Most importantly it is how fast we can find cures for diseases
and maybe even save lives.

Below I have compiled some usefull links on Folding @ Home:

Folding @ Home official web-site:
To find out more information:
To find out all the teams stats:
To find out fellow Overclockers.com members stats:
(See all the Overclockers.com members already Participating)
Overclockers.com Folding @ Home Web-Site:

I hope you have chosen to participate in the Folding @ Home

If you have any questions or comments please post them!
Or feel free to PM me or one of the other Folding @ Home Participants!

- Overclockers.com Folding @ Home Participants and Stanford University


This section applies if you have chosen to participate:

Download Folding @ Home software.

Once you have downloaded the program install it,
during the installation it will ask you for some information:

First it will ask you for your, Name or E-mail
In this blank put your registered overclockers.com name
Example: My name is YMAN so I put YMAN in the space provided.

Second it will ask you for a Team Number or team.
If 32 is not put in the space provided, you will not be considered
an Overclockers.com member in the Folding @ Home project!!!!

After the installation the program will automatically start.
Once started if will keep folding until you shut it off or exit your
operating system! Best of all you will not know that it is running!
- Folding @ Home only uses your extra, currently wasted CPU cycles!

If you have any questions or comments please post them!
Or feel free to PM me or one of the other Folding @ Home Participants!

- Overclockers.com Folding @ Home Participants and Stanford University
Last edited:
If you downloaded the graphic version please turn off the screansaver under your display properties. It is actually a little slower than just letting it run in the background. Welcome to the Fold:D If you have any questions just ask in the F@H section of these forums.
and remember that even if you use linux, you can still contribute to the folding cause! stanford has been gracious enough to produce a linux version (which has a recently released beta, which is folding on my computer as we speak). it is really excellent..just text based (which is IMO better)...i just put it on one of my 4 desktops with my gkrellm hardware monitor running and i literally couldn't know it was running if i didn't start it up myself! honestly, i can think of no better way to contribute to a good cause such as this...especially considering that my mother has alzheimers and this can help in finding a cure. so please, as an overclocker, use the extra cpu cycles that your beast produces to help out on this GREAT project, and have fun participating in the points race, too ;)

Dragonbud said:
also to mention, its a superb burning-in and benchmarking platform.

Very true, it keeps your CPU loaded 100% for 100% of the time. Let that Arctic Silver fill the pores by heating it up...fold some proteins!
Feel free to ask questions about Folding@Home in the Folding@Home forum - there are loads of people who would be pleased to help out.

If you can get folding at your school or work - fantatic!
Make sure that you get permission - this is very important.
Wtg guys, think you've pretty much covered it all. Hope this helps to get the word out.
Anyone reading this, please consider helping us, it is a very well designed program that truely does stay in the background and hardly ever affects anything else the computer might be doing, yet still manages to utilize as much available cpu cycles as can be had.
Plus quite a few of our members have been brain stormin to try and develop little contests just for the members of team 32 that really helps with the motivation to ultimately help with the big picture, and they're doing it out of their own pockets. How much more dedication can you get than that? ;)
The crew that heads the project for team 32 are knowledgable and very helpful in helping to setting up program (ITS REALLY EASY THOUGH.. TAKES ABOUT 5 MIN TO SETUP).. And its for a great cause! So come one come all to O/C.com team 32 and help us fold our way to a cure for genetic diseases!
Also to you Mac users that are running OSX, there is a Folding@Home client for you to run now. It is also available on the same download page as the Windows and Linux clients. I'd like to see how the Mac's can process these work units compared to the x86 machines that I am using.
Re: Want to help the world? Look here!! Folding Team32

Ploaf said:
Only two are outproducing us at the moment and we could use your help to retake the lead that we once had.

Three. Sorry - I had to point this out. We have to really boost production to stay 3rd - Team rage 3D are hot on our tail, producing nearly 25% more than us each week.

This is the best computing forum on the net. Lets make it the best folding at home team as well!
Re: Re: Want to help the world? Look here!! Folding Team32

David said:

Three. Sorry - I had to point this out. We have to really boost production to stay 3rd - Team rage 3D are hot on our tail, producing nearly 25% more than us each week.

I don't know what you're talking about ;) j/k It's fixed

BTW. We just tapped a new keg of :beer: in the Folding Forum

Stop on by. Hook up with 50, 100, 250, 500, 1000, 2500, 5000, or so points and we will open the tap. :D

Fold On :burn:
Re: Re: Re: Want to help the world? Look here!! Folding Team32

Ploaf said:

I don't know what you're talking about ;) j/k It's fixed

BTW. We just tapped a new keg of :beer: in the Folding Forum

Stop on by. Hook up with 50, 100, 250, 500, 1000, 2500, 5000, or so points and we will open the tap. :D

Fold On :burn:

And thats talking my language!:beer: If the spirit of these guys aren't enough to convince you, try reading the home page for Folding@Home. It explains exactly what it is doing and explains what the procedure hopes to gain from it. :D
i have a question

are the points based on how long it takes?
on my 1.4ghz XP it took a perdy long time and
gave me about 4 points a WU. now i do like 1 every
hour or so and i only get about 1 point per WU.

is this normal? thanks :p
Welcome to the team Diehrd!
The best answer for your question will probably be found within the Folding Section of the forums.
There have been a number of people recently running dual cpu systems there lately.

Starfox - The points are determined by the size and complexity of a protein and how long the protein takes to complete. The longer the protein takes, the more it's worth. The proteins are benchmarked using the same system to help ensure consistency in scoring. The scoring of the proteins is not cpu dependent however. A ProteinA that returns 5 points for a 2000XP will return 5 points for a 400MHz Celeron despite the fact that the celeron takes longer to do the work. That is becuase the proteins are the same size for each system.
Well Over in the Folding part of this form we have been having a contest for a new Xp1600 Processor and the final standing are in you can get more info on the contest at Overclockers Forums Folding Contest

There will be more contest down the road some come help us fold and help the world! You might even win something for your trouble :)
Could anyone participating in Folding@Home check out the sticky in F@H folding - please add your folding GHz.
Just a reminder we also have a team within the main team. It is still team 32. It is Yatta. It is a collection of computers between 200 and 500. This team is just starting out so please if you have a computer in this range please configure it to Yatta on team 32. The goal of this team is to compete with the regular folders and to motivate our members to pick up production.
Fold on!!!!!!
The contest starts on the 20th!!!!!:bday:
Hurry up and enter all it takes is to click the yellow link in my sig. and PM Cluster and Fold for the best Folding team in the world!!!:D that is it you are in. Enter the contest to win your choice of a Duron or Celeron processor!!!!