Here is a good read.
"Perhaps one of the biggest pitfalls of MBR-based disks is their potential for corruption of the partition table, a region on the disk that maps sectors to logical block numbers. MBR disks only have 1 partition table to keep track of all the blocks in the partition. If the table becomes corrupt, the entire disk must be recovered from backup. Windows GPT-based disks have multiple, redundant partition tables so that if one is detected as being corrupt, it can self-heal itself from a redundant copy of the table.
Despite the many advantages of GPT-based disks over MBR drives, many vendors still utilize the MBR technology since it is still predominantly used in the real world. GPT disks are gaining popularity with their benefits in terms of partition size, number of partitions, and resilience. Windows Failover Clusters now support GPT-based disks which will broaden their use in enterprise data centers. See related article on Failover Cluster Setup. So while bigger isn’t always better, the many advantages of GPT-based drives make them an attractive alternative."
http://www.petri.co.il/gpt-vs-mbr-based-disks.htm