Only way to find out, hehe... is benchmark! Try running a memory bandwidth test from Sandra or Everest with either of those settings.. one should yield slightly better results by the end. I think even Dolk's guide goes into a bit of memory tests and running at 1333 with tighter timings ended up giving him more bandwidth than 1600 and a looser timings.
I need to stop being lazy and fine-tune my memory..