One time I powered up a Syntax (aka ECS) S635MP (not so good board with integrated VIA CPU) without the memory. I put it back in and it wouldn't boot. But I reset the CMOS and it then worked fine. So be aware of that if it may stop working.
Kind of a long story but the short version is;
I needed to check mobo voltage on vdimm, core and I knew it was ok w/o memory in, but the only cooling I had at that point was my RBX which wasn't set up yet.
Anyway, it went fine but I didn't want to take chances on frying my board when I could just ask first.
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