Well, nothing really has to be turned off to overclock. Usually people suggest turning off cpu spread spectrum and pci spread spectrum - so you can disable those. They also suggest turning off power savings - if you aren't sure which options are power savings features, then you can reference the rog bios guide. I also disabled everything under the advanced CPU features page, like virtualization, HPC mode, et cetera - none of that is needed for most desktop usage (unless you run vmware or virtualbox).
Other than that, here is a super easy overclocking guide:
1. Leave all other settings at default, unless stated otherwise. Monitor temps not letting them get too high throughout the following steps - if temps are too high, don't increase voltage further until you get better cooling
2. Boot into bios, and view your core voltage reading - that is the VID of your chip. Then increase vcore by .1V
3. Increase CPU multiplier by .5, rebooting to see if it can boot, repeat until it doesn't
4. If you aren't at 4.5GHz yet, increase vcore by .05V
5. Increase CPU multiplier by .5 until you are at 4.5GHz, or until it can no longer boot
6. Once you have your OC where you want it, start with prime95/stress testing to see if its stable
7. You will probably need to fine tune your voltages, and tweak the settings under digi+vrm to get it stable under load
Do you have the system now and are you able to try that? Just post back and let us know where you get stuck as you try it, we'll get you there.