I've been out of the loop for a while

Which GPU client should I be using for a GTX260 core 216?

Is it the first GPU2 client on this page? (I'm running Windows 7 64 bit)
http://folding.stanford.edu/English/DownloadWinOther

People seem to have better luck running the console version (so second GPU2 client on that link). But you can run the GPU3 client if you like. You will mostly still get the same WU's that GPU2 is dishing out since it favors the new WU's on Fermi hardware. But you could still get the new wu's. I'm not sure about the PPD difference between the old batch and the new batch of wu's between GPU2 and 3.