I run 5x 250GB Samsung 970 Evo/NVMe R0 in my gaming PC ... just because I had 5x 250GB SSD after tests that aren't worth selling and the motherboard has 5x M.2 3.0/4.0 without any weird add-on cards. Btw. it's Gigabyte Z690 Master. If not the RAM support then I would say it's a great mobo