I generally run only ClamWin free. It does not scan anything unless you tell it to. I use BleachBit to clean temp files.
As for the Chrome browser, there's talk it may change it's api's manifest so that ONLY Adblock Plus's filters will work and it will be limited to 30,000 entries which in and of itself is a joke. This will break all other adblockers such as umatrix and ublock origin completely. It is not yet implemented as far as I know but is something to think about when choosing a browser. For the best security, DO NOT rely upon someone else giving it to you on a platter. I do NOT recommend adblock plus on any machine for any reason. Ublock origin (for mobile & desktop) simply downloads lists and uses the files locally as a browser extension. This puts the control in your hands and not in google's, MS's, Mcaffee's, norton's, symantec's, whoever. Any so-called AV software that is constantly scanning your files is in and of itself a security risk when it's always connected to a remote server (anything made by comodo is a prime example of who NOT to trust). Clamwin does not do this as it acts just like ublock origin does. It downs the latest lists and only connects to check for any newer security updates. In fact that is all it does automatically is update the virus list.
A good example of why corporations like google are actually "bad for business" is facebook's new "bitcoin" scheme. Facebook wants to offer it's own bitcoin to the entire planet. Bitcoin was created for the sole purpose of bypassing the corrupt banking system that the US controls and uses to intimidate and coerce entire countries with. Facebook's fakeass "bitcoin" is simply the same banking system sold as a secure cryptocoin, this so that they can continue to stay in control of everything people do monetarily.
In essence, one must do everything one can without involving the retards (middlemen/third parties) who think they should be the sole supplier, sole source, of whatever it is you think you need.
https://www.ghacks.net/2019/01/22/chrome-extension-manifest-v3-could-end-ublock-origin-for-chrome/