I have an antec case with front and rear fan (unsure what model) and recently I found that I had the side panel with ventilation holes on the wrong, motherboard chassis side. I swapped them over and found it was a lot noisier that way. I've swapped them back, and I'll just note that while the holes are over the cpu heatsink, there's no room for fans or anything on the inside of the case. Is having no ventilation there a big no-no?