g0dm@n:
Whatever you go with, make sure that it's a x38 or x48 north bridge, for the dual full 16x PCIe slots. I just read a review comparing dual 8x to dual 16x lanes (P45 vs X48) with crossfire 4850's. Surprisingly enough, even though they are PCIe 2.0 spec, and therefore double the bandwidth of PCIe 1.1, it did make a difference to get the full dual 16x over the dual 8x. I want to say it was somewhere around a 5 - 8% difference. I can't find the article right this minute, but I'll post back and edit as soon as I find it!
Also, you're sure the Zalman VF900's fit on the 4850's? I was looking to upgrade to dual 4850's and get an ABIT IX38 motherboard to go with them. And I was really hoping that the VF900's would work the the 4850's. If you could confirm this, you'd make my day!