The sad part is...without the extra .5 multi some of us won't max the chip out. I've always been happy with a 9 multi (AMD64 3000+, Opty165, E6600), but now to max a chip out we might need a 10x multi or a mobo/ram than can do some work on the positive side of 500 fsb.
I'm definitely going to be FSB limited by the 45nm process. I doubt my ram can run past 450mhz, I've actually never ran it that high. So 450x9 gives me 4ghz. That should be a breeze on air cooling, let alone water. I might end up selling my watercooling and combining that with my upgrade budget to get a 10x multi. Who knows...