I guess you could cool the motherboard, like the southbridge/northbridge chipsets, however keep this in mind, if you hook the cpu,nb,sb in series with your watercooling rig, the end of that chain will probably be getting hot water so unless you want to have separate radiators,pumps, and lines then just get some blue orbs, some arctic silver epoxy, and epoxy them onto the chipsets directly. I use that on my kt7a and I can hit 152fsb with pc133 ram.