If your using the NF7-S Thats in your sig, the CMOS battery, and clrcmos jumper is in that area. If you fired up the board in the clear cmos position, that would cause your puff of smoke.
Not that I like to admit it, but I'm guilty of that myself. Luckily, when I put the jumper back where it belonged, the board was just fine. I've heard a couple of stories where people weren't so lucky after the mishap though.
Hoping for a happy ending!