Looks like you need better cooling, you're at the end of your OC with those temps.
You may want to try blending @ 4.3 with a little more vcore, because you 4.2 run is using 1.4 vcore. Your game is crashing because your cores are unstable, not because the game is having issues.
For MY motherboard, in order to hit 4.2, I have to add just a HAIR of voltage to it. We're talking 1.39 vcore to get it to go stable for 2 hours @ 4.2ghz.
MY stats for 4.4ghz are 1.46 vcore, 1.25 NB, 22x multiplier. You might want to try something SIMILAR to what I do to get 4.5, which is 1.49 or 1.5 vcore. Like I was saying in the beginning, you're going to need better cooling, or a cooler room, to overclock anymore than 4.2ghz.
edit;
To answer your question, I bet it's a motherboard problem. Your photo there is a 4.2 ghz run at 1.4 vcore, so it's impossible for you to run stock speeds at 4.3ghz.