I have helped find sticks that did not reach tested speed in threads you have been in, one guy if you can remember purchased 3 sets of the same G.SKILL before XMP worked on all 4 . Testing factory overclocked memory is a lost art, folks now just settle for lower speed or loos timings with factory overclocked memory. The OPs motherboard is rated SS DDR4 64GB at 4200 speed, If it was me I would check the new memory.
This is for KabyLake-X , not Skylake-X. Even if 4000+ is on the list then believe me, nearly all manufacturers were lying in their QVL lists giving the same max frequency for all their motherboards regardless of used CPU or memory setup. ASUS made exactly the same list for every single X299 motherboard. In real barely anyone tested it with memory at more than 3600. They even made OC guide where they said that max they can guarantee on X299 is 3600 ( maybe there is something new but I doubt ).
Next thing is that everything above 2133 is marked as OC so not guaranteed.
However there are all ... 2! memory kits on the G.Skill website ( not counting different colour ) tested at 4000+ on ASUS Rampage VI. Still to make it run like that there have to be perfect timings.
Check OC rankings and you will see that top scores on X299 are near 4133... as max that will boot or pass quick tests, not stable. If it could run much higher then people would do that.
There is a chance that OP memory will make 4000-4133 on this motherboard but it will require manual settings. This will require some knowledge and a lot of time spent on tests while final effect won't be much better than what this memory offers at ~3600 and tighter timings.