Well, I take it that Hoot's comments, and the whole direct die movement are motivated by the idea that you want the thinnest possible base so that the heat transfers across it quickly and efficently. Thick bases are motivated by the idea that the base acts as a sink, a holder for the heat, and it dissipates it across a wider area.
By using a graduated base, I would hope to attain the best of both worlds. I would get very efficient transfer at the center while still allowing the heat to spread outward and allow a greater area for cooling. Additionally the graduated design should allow me to get thinner at the center because I would still have the structural support of the somewhat thicker area at the edge of the core.
My thought is to try a multi-armed spiral, with one arm beginning at each of four corners converging to a central chamber just above the core. I'd probably run the flow from the edge to the center in order to take advantage of (some process whose name I can't recall, but basically where you use the coldest water to cool the cooler parts and as it warms you use it to cool the hotter parts).
Keep in mind this is entirely theoretical. I'm not an engineer, nor do I play one on TV. And I don't even own a water pump (yet).
nihili